No puppy, or dog for that matter, should be left alone for long periods of time. Dogs that are left alone for significant periods can develop anxiety and an inability to cope with being separated from their owners.
You can easily teach your puppy to tolerate short absences by leaving him in a room, closing the door and walking away. After a few minutes, go back in but don't greet him. When you've done this several times, extend the absences to 30 minutes. But if he begins to get distressed, and starts barking, chewing, or scratching at the door, you should shorten the absence period.
Before you leave, try these simple tips to help your puppy settle down while you are out:
If your puppy has growing concerns about being left alone, even for short periods of time, ask your vet for advice.